About Wet AMD

What is
wet AMD?

Wet age-related macular degeneration (wet AMD) is a chronic eye disorder, resulting in symptoms that can quickly get worse. It is one of the leading causes of vision loss in people aged 50 years and older. With early detection and treatment, symptoms may be managed, and in some cases, vision may be improved.

Inside an eye
with wet AMD

In the wet form of age-related macular degeneration, extra blood vessels form and leak blood and fluid in the back of the eye.

Wet AMD develops when abnormal blood vessels grow under the macula, which is the part of the eye that is responsible for central vision and seeing detail.

These blood vessels leak blood and fluid in the back of the eye.

This can scar the macula, causing symptoms such as blurred vision, wavy lines, dull colors, or blind spots.

Who’s at risk for developing wet AMD?

While the exact causes of wet AMD are unknown, certain factors have been found to put people at greater risk for developing wet AMD, such as:

If you are aged 65 years or older, then you are at greater risk for developing wet age-related macular degeneration. If you are aged 65 years or older, then you are at greater risk for developing wet age-related macular degeneration.

Age

If you have a family history of wet age-related macular degeneration, then you are at greater risk for the condition. If you are aged 65 years or older, then you are at greater risk for developing wet age-related macular degeneration.

Family history
of wet AMD

If you smoke, then you are at greater risk of developing wet age-related macular degeneration. If you smoke, then you are at greater risk of developing wet age-related macular degeneration.

Smoking

How can wet AMD change your vision?

Wet AMD can affect your vision in a number of different ways. You may find that these vision changes can interfere with everyday activities, such as reading, writing, household chores, and the ability to see faces.

Click the tabs to explore the different types of vision changes. Drag the slider to see the varying symptoms.

Central
vision

Lines

Color

Size/
shape

What does a person with wet age-related macular degeneration see? You may see blurry/blind spots appear in the center of your vision.
What does a person with wet age-related macular degeneration see? You may see blurry/blind spots appear in the center of your vision.

Blurry or blind spots can appear in the center of your vision.

What does a person with wet age-related macular degeneration see? Straight lines may look bent or wavy.
What does a person with wet age-related macular degeneration see? Straight lines may look bent or wavy.

Straight lines can look bent or wavy.

What does a person with wet age-related macular degeneration see? Colors may look faded and/or washed out.
What does a person with wet age-related macular degeneration see? Colors may look faded and/or washed out.

Colors can look faded and/or washed out.

What does a person with wet age-related macular degeneration see? Objects may appear the wrong size or shape.
What does a person with wet age-related macular degeneration see? Objects may appear the wrong size or shape.

Objects can appear to be the wrong size or shape.

Wet AMD symptoms and progression affect everyone differently. If you’re experiencing any of these symptoms, talk to your doctor right away

Lifestyle tips to help manage wet AMD

Research suggests making a few lifestyle changes may slow the progression of wet AMD:

Eating healthy can help lower your risk of developing wet age-related macular degeneration.

Eat healthy

Eat a nutritious diet with plenty of vitamins and minerals,
often found in green, leafy vegetables.

Regular physical activity can help lower your risk of developing wet age-related macular degeneration.

Stay active

Regular physical activity can help keep your eyes healthy.

If you smoke, quitting can significantly help lower your risk of developing wet age-related macular degeneration.

Do not smoke

Quitting smoking may help slow vision loss. Ask your
doctor for help to quit.

Wet age-related macular degeneration can worsen over time. So stick to your treatment plan and see your doctor regularly.

Stay on track with your treatment plan

Be sure to follow your treatment plan and see your
doctor regularly.

Learn more See how BEOVU may help

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INDICATIONS

IMPORTANT SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

COLLAPSE

EXPAND

BEOVU® (brolucizumab-dbll) injection is used for the treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME).

You should not use BEOVU if you have an infection in or around the eye, eye inflammation, or if you are allergic to brolucizumab or any of the ingredients in BEOVU.

BEOVU is a prescription medicine given by injection into the eye. Injections in the eye, including BEOVU, may cause an infection of the eye or retinal detachment (separation of retina from the back of the eye). It is important to contact your doctor right away if your eye becomes red, sensitive to light, painful, or you develop any change in your vision.

Increased eye pressure has been seen within 30 minutes of an eye injection, including BEOVU. Sustained increases in eye pressure also have been reported. Your doctor should monitor for this when you receive a BEOVU injection.

There is a potential risk of stroke, heart attack, or blood clots in patients receiving eye injections of vascular endothelial growth factor (VEGF) inhibitor drugs, including BEOVU. Sudden vision loss due to blockage of the blood vessels in the back of the eye and inflammation of blood vessels in the back of the eye have been reported.

The most common side effects reported in patients receiving BEOVU in the wet AMD studies were reduced clarity in vision, cataract, broken blood vessels in the eye, eye pain, and vitreous floaters (moving spots in the field of vision). The most common side effect reported in patients receiving BEOVU in the DME studies was broken blood vessels in the eye.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.

Please see full Prescribing Information.

INDICATIONS

BEOVU® (brolucizumab-dbll) injection is used for the treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME).